{"id":2962,"date":"2022-11-14T01:19:08","date_gmt":"2022-11-14T00:19:08","guid":{"rendered":"https:\/\/www.snamiroma.org\/wp1\/?p=2962"},"modified":"2022-11-14T01:19:10","modified_gmt":"2022-11-14T00:19:10","slug":"considerazioni-sulla-nota100-e-luso-degli-antidiabetici-orali-in-italia","status":"publish","type":"post","link":"https:\/\/www.snamiroma.org\/wp1\/2022\/11\/14\/considerazioni-sulla-nota100-e-luso-degli-antidiabetici-orali-in-italia\/","title":{"rendered":"Considerazioni sulla Nota100 e l\u2019uso degli antidiabetici orali in italia"},"content":{"rendered":"\n<p class=\"has-text-align-justify wp-block-paragraph\">La prescrizione degli inibitori del SGLT2, degli agonisti del recettore GLP1, degli inibitori del DPP4 e loro associazioni <span style=\"text-decoration: underline;\">sono regolate dalla NOTA 100 di AIFA<\/span>. <strong>Il diabete non \u00e8 solo un disturbo associato a scarso controllo della glicemia ma in una sovrapposizione di pi\u00f9 elementi fisiopatologici si associa a complicanze micro e macrovascolari che causano cardiopatia ischemica, ictus, neuropatia e retinopatia<\/strong>. La riduzione dei valori della glicemia non \u00e8 sufficiente a migliorare gli esiti a lungo termine della macroangiopatia e non incide sull\u2019insorgenza delle complicanze e sulla mortalit\u00e0.<\/p>\n\n\n\n<p class=\"has-text-align-justify wp-block-paragraph\">Diversi studi clinici randomizzati hanno dimostrato per gli inibitori del SGLT2 e gli agonisti recettoriali del GLP1 rilevanti benefici in termini di riduzione degli eventi cardiovascolari maggiori e della mortalit\u00e0 cardiovascolare nei pazienti con malattia cardiovascolare accertata o multipli fattori di rischio oltre che un miglioramento del controllo glicemico senza ipoglicemie. Pertanto la <strong>Nota100 recepisce le indicazioni delle linee guida che hanno evidenziato l\u2019opportunit\u00e0 di intraprendere un trattamento con i farmaci in nota gi\u00e0 in prima linea<\/strong>, definisce i criteri di inclusione al trattamento, dando la possibilit\u00e0 a tutti i medici di intraprendere un trattamento con incretine, glifozine e gliptine, favorisce il rapido arruolamento dei pazienti, senza aspettare i tempi biblici delle liste d\u2019attesa, \u00e8 una opportunit\u00e0 di curare meglio i pazienti diabetici.<\/p>\n\n\n\n<p class=\"has-text-align-justify wp-block-paragraph\">Maggiori dettagli sono nel documento allegato che invitiamo tutti i colleghi a leggere e diffondere.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Documenti allegati:<\/h3>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2022\/11\/VADEMECUM-NOTA-100-DEFINITIVO.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Incorporamento di VADEMECUM-NOTA-100-DEFINITIVO.\"><\/object><a id=\"wp-block-file--media-bad8d4aa-939a-4074-9cc3-2ec1dd647cb9\" href=\"https:\/\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2022\/11\/VADEMECUM-NOTA-100-DEFINITIVO.pdf\">VADEMECUM-NOTA-100-DEFINITIVO<\/a><a href=\"https:\/\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2022\/11\/VADEMECUM-NOTA-100-DEFINITIVO.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-bad8d4aa-939a-4074-9cc3-2ec1dd647cb9\">Download<\/a><\/div>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\"\/>\n\n\n<ul class=\"wp-block-latest-posts__list is-grid has-dates aligncenter wp-block-latest-posts is-layout-flow wp-block-latest-posts-is-layout-flow\"><li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2024\/11\/logo_snamiLazio_regular-1.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2024\/11\/logo_snamiLazio_regular-1.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2024\/11\/logo_snamiLazio_regular-1.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2024\/11\/logo_snamiLazio_regular-1.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/09\/21\/in-memoria-di-paolo-nobili\/\">In memoria di Paolo Nobili<\/a><time datetime=\"2026-09-21T14:43:49+02:00\" class=\"wp-block-latest-posts__post-date\">21\/09\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">La Sezione SNAMI di Frosinone \u00e8 profondamente scossa e addolorata dalla notizia&hellip;<\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/09\/89695869.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/09\/89695869.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/09\/89695869.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/09\/89695869.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/09\/07\/certificati-di-malattia-le-nuove-indicazioni-inps-dal-4-settembre-2026-esteso-anche-alle-visite-ambulatoriali-il-riconoscimento-del-giorno-precedente\/\">Certificati di malattia: le nuove indicazioni INPS dal 4 settembre 2026 \u2014 esteso anche alle visite ambulatoriali il riconoscimento del giorno precedente<\/a><time datetime=\"2026-09-07T17:13:42+02:00\" class=\"wp-block-latest-posts__post-date\">07\/09\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">Con la Circolare n. 92 del 4 settembre 2026, l&#8217;INPS estende anche&hellip;<\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/02\/logo_snamiroma_2026_large_rid.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/02\/logo_snamiroma_2026_large_rid.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/02\/logo_snamiroma_2026_large_rid.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/02\/logo_snamiroma_2026_large_rid.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/09\/06\/stipendi-in-ritardo-per-i-medici-delle-case-di-comunita-la-protesta-di-snami-roma\/\">Stipendi in ritardo per i medici delle Case di Comunit\u00e0: la protesta di SNAMI Roma<\/a><time datetime=\"2026-09-06T13:17:04+02:00\" class=\"wp-block-latest-posts__post-date\">06\/09\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">SNAMI Roma protesta con la ASLRM6 per il mancato pagamento delle ore&hellip;<\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/07\/dott_giuseppe_di_donna.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/07\/dott_giuseppe_di_donna.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/07\/dott_giuseppe_di_donna.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/07\/dott_giuseppe_di_donna.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/07\/26\/in-memoriam-dott-giuseppe-di-donna\/\">IN MEMORIAM: Dott. Giuseppe Di Donna<\/a><time datetime=\"2026-07-26T23:30:00+02:00\" class=\"wp-block-latest-posts__post-date\">26\/07\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">In Memoriam | Oggi apprendiamo della perdita del nostro amato amico e&hellip;<\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/07\/07\/tar-lazio-sentenza-n-11984-2026-illegittima-la-prescrizione-suggerita-che-vincolava-i-medici-di-famiglia\/\">TAR Lazio sentenza n. 11984\/2026: illegittima la &#8220;prescrizione suggerita&#8221; che vincolava i medici di famiglia<\/a><time datetime=\"2026-07-07T11:44:30+02:00\" class=\"wp-block-latest-posts__post-date\">07\/07\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">L&#8217;avv. Beatrice Lucarelli, legale di #SnamiRoma e #SnamiLazio, ci ha segnalato ed&hellip;<\/div><\/li>\n<li><div class=\"wp-block-latest-posts__featured-image aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=150%2C150&amp;ssl=1\" class=\"attachment-thumbnail size-thumbnail wp-post-image\" alt=\"\" style=\"\" srcset=\"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2026\/05\/8582393433309433.jpg?zoom=3&amp;resize=150%2C150&amp;ssl=1 450w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/div><a class=\"wp-block-latest-posts__post-title\" href=\"https:\/\/www.snamiroma.org\/wp1\/2026\/05\/23\/maternita-e-stabilizzazione-la-corte-costituzionale-n-76-2026-retrodata-il-diploma-mmg-per-la-trasformazione-dellincarico\/\">Maternit\u00e0 e stabilizzazione: la Corte Costituzionale (n.76\/2026) retrodata il diploma MMG per la trasformazione dell&#8217;incarico<\/a><time datetime=\"2026-05-23T01:10:34+02:00\" class=\"wp-block-latest-posts__post-date\">23\/05\/2026<\/time><div class=\"wp-block-latest-posts__post-excerpt\">L&#8217;avv. Beatrice Lucarelli, legale di #SnamiRoma e #SnamiLazio, ci ha segnalato ed&hellip;<\/div><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>La prescrizione degli inibitori del SGLT2, degli agonisti del recettore GLP1, degli inibitori del DPP4 e loro associazioni sono regolate dalla NOTA 100 di AIFA. Il diabete non \u00e8 solo un disturbo associato a scarso controllo della glicemia ma in una sovrapposizione di pi\u00f9 elementi fisiopatologici si associa a complicanze micro e macrovascolari che causano&hellip;<\/p>\n","protected":false},"author":1,"featured_media":828,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[60,106,21,55,15,56,18,57,29,30,3,13,62,14,746,87],"tags":[132,35,625,626,624,493,627,623],"class_list":["post-2962","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aifa","category-appropriatezza-prescrittiva","category-assistenza-cure-primarie","category-assistenza-primaria","category-comunicazioni-iscritti","category-continuita-assistenziale","category-documenti","category-medicina-dei-servizi","category-medicina-e-innovazione","category-ministero-della-salute","category-news","category-regione-e-asl","category-regione-lazio-dispositivi-e-circolari","category-sezioni-provinciali","category-snamilazio","category-unita-cure-primarie","tag-aifa","tag-diabete","tag-diabete-mellito","tag-diabete-mellito-di-tipo-2","tag-farmaci","tag-guida-ufficiale","tag-metformina","tag-nota100"],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_likes_enabled":true,"jetpack-related-posts":[],"jetpack_shortlink":"https:\/\/wp.me\/pb3IKS-LM","jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.snamiroma.org\/wp1\/wp-content\/uploads\/2020\/02\/logo_snami_Roma_progetto_v001.svgz_grande.png.jpg?fit=1093%2C620&ssl=1","_links":{"self":[{"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/posts\/2962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/comments?post=2962"}],"version-history":[{"count":1,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/posts\/2962\/revisions"}],"predecessor-version":[{"id":2964,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/posts\/2962\/revisions\/2964"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/media\/828"}],"wp:attachment":[{"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/media?parent=2962"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/categories?post=2962"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.snamiroma.org\/wp1\/wp-json\/wp\/v2\/tags?post=2962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}